The Revolutionary Association of the Women of Afghanistan (RAWA)
RAWA has remained an organization throughout the Soviet occupation and war, the Taliban take over, and the current United States occupation and war. They have opened up orphanages, schools, and hospitals throughout Afghanistan and refugee camps in Pakistan. They provide literacy courses to adults and help with food distribution to the Afghan people as well as counseling and job training to women forced into prostitution. You can see all they have accomplished here or read the book With All Our Strength: The Revolutionary Association of the Women of Afghanistan by Anne E. Brodsky.
RAWA provides several options for helping out financially. You can donate directly through their site, purchase books, shirts through their cafepress, or fund something from their amazon wishlist (the cameras and electronics are used by Afghan women to secretly film the atrocities committed throughout the country).
There are also ways to help out without opening your pocketbook. RAWA lists them here. For example, talking to local leaders about bringing a RAWA representative to your area, translating articles into other languages, or having a teach-in about RAWA and Afghanistan in your community.